Connective Tissue

connective tissue that surrounds tissue component of organ

functioning part of organ

• mechanical support and protection of soft tissue • physiological support (molecular exchange) a. forms a pathway for blood vessels and nerves b. fluids of connective tissues act as a medium of exchange for metabolites between tissues and blood vessels • storage of energy in the form of fat • defense against infection • repair of injuries • maintain boundaries • cell adhesion and movement

fibres, ground substance, cells

aqueous, tends to be removed

round and squiggly; inelastic; tensile strength; storage of strain energy; abundant

thin; when pulled taut, have sharp angles; can also be squiggly

molecule - glycine, proline, hydroxyproline triple helix fibril - bundle of triple helices fiber - bundles of fibrils tissue - tendon, bundles of fibers

type 1 - fibrils, bones, tendons type 2 - cartilage type 3 - reticular fibers type 4 - nonfibrillar (basement membrane)

• strech • flexibility • branched • fenestrated sheets

• glycosaminoglycans (GAGs) - proteoglycans

• molecular highway/parking lot • molecular exchange • hydrating molecles • more = looser • nutrient delivery • cell movement (plasma, mast cells)

• fibroblasts • macrophages • plasma cells • mast cells • leukocytes • adipocytes

synthesize matrix wound healing

dense nuclei in connective tissue large nucleus = active

thin dense nucleus

called monocyte in blood v good at endocytosis (particle and dye)

primary immune response histamine large cells - red/purple granules

b-lymphocyte in blood make antibodies (sometimes see golgi bc they're working so hard) large nucleus (clock face) --> heterochromatin

• neutrophil • eosinophil • lymphocyte

unilocular, multilocular

dynamic energy storage white fat

brown fat - for hibernation - in bears and such hella mitochondria

connective tissue proper, specialised connective tissue, and supporting connective tissue