Tumor Markers (Part 3)

What is useful in the detection of pancreatic and colorectal cancer

used as a marker for multiple myeloma for over 100 years

Histological marker for melanoma and melanoma metastases

Used to diagnose differentiated thyroid cancer

Used as indicators for therapy in breast cancer

Neuroblastoma and AML and 95% of pancreatic cancers

If activated, there is an association with B- and T-cell lymphoma

Amplification is found in breast tumors and used for prognosis

Expressed in lymphomas, myeloma, and chronic leukemias

Useful in the diagnosis and in the directing of treatment in CML

Loss of banding on this gene leads to a rare pediactric tumor called retinoblastoma

Deletions in this gene may bead to colon carcinoma

Loss leads to colorectal cancer with or without many polyps

Reasonably certain prediction that the woman will develop breat (85% of patients) or ovarian cancer (45%) by the age of 85