Final Pt. 2
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What is a operon?
unit of genetic function found in bacteria, consisting of a promoter (more than one gene) , an operator (ON/OFF switch), and a coordinately regulated cluster of genes whose products function in a common pathway
Inducible vs. Respressible operon
Inducible- usually off, turn on (catabolic) Repressible- usually on, repress (anabolic)
steps of TRP repressible operon?
• up tryphotfan • active trp repressor, binds to operator • low transcription by RNA Poly 3 • low trp pathway enzymes • low trp systheisi
steps of lactose inducible operon?
• up lactose • up allolactose, binds to repressor • down active lac repressor • up transcription by RNA Poly 3 • up lactose enezyme path • up hydrolysis of lactose to glucose
allosteric inhibtion?
binds to inactive form of portein to keep inactive
histone aceytlation?
increases avlibtliy of euchromation
histone methylation?
decreases avalibility of DNA- more heterochromatin
DNA methylation often occurs in-
logn stretches of C and G