Lect. 3 Carbohydrates
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Glucose
Used in polymer synthesis (monosaccharide)
Fructose
Component of table sugar (monosaccharide)
Galactose
Component of milk sugar (monosaccharide)
Ribose (Type)
Used in RNA nucleotides Component of RNA
Deoxyribose (Type)
Used in DNA nucleotides Component of DNA
Sucrose
In plants, table sugar di-saccharide glu + fru
Lactose
Milk sugar di-saccharide glu + gal
Maltose
Brewing sugar di-saccharide glu + glu
Starch
Storage in plants polysaccharide
Glycogen
Storage in animals polysaccharide
Cellulose
Structural in plants polysaccharide
Chitin
Structural in animals in fungi polysaccharide
Peptidoglycan
Structural in bateria polysaccharide
2 types of sugar
aldoses and ketoses difference lies in the location of the carbonyl gr. (-C=O)
Monosaccharide molecular formulas
multiple of CH2O (1:2:1 ratio) [CH2O]n where n is a nber between 3 and 7
3 most common sugars
• Trioses (smallest sugars) • Pentoses (in DNA) • Hexoses (common sugars)
3 common monosaccharides (all hexoses)
• glucose • galactose • fructose all 3 have chemical formula: C6H12O6 they are structural isomers of one another
most common monosaccharide
glucose its open chain forms of glucose form ring structures in solutions ring form is the most common form in living organisms
How does glucose form rings? What is the ring called?
C1 aldehyde reacts with C5 hydroxyl gr. to form a ring called a pyranose ring
2 isomers of glucose ring structure
• α-glucose, OH gr. at C1 is on the opp. side of CH2OH • β-glucose, OH gr. at C1 is on the same side as CH2OH these isomeric forms differ in the orientation of the OH gr. at C1
Glucose in Biology Glucose is the end product of what process? What is it used for?
• Photosynthesis in plants • Glucose is used as an energy source in most organisms During cellular respiration, cells oxidize glucose molecules converting the stored energy to a form that can be readily used for cell work.
Homeostasis of Blood Glucose What regulates the concentration of glucose in the blood? Where is it produced?
Hormones insulin and glucagon which are produced by the pancreas transported thoughout the body via blood vessels
Almost all mechanism to maintain homeostasis:
negative feedback mechanisms return a variable to its set point loop: set point, stimulus -> detected by a sensor -> triggers response to return to the set point (effector)
What does insulin do?
Insulin decreases blood glucose. Insulin can bind to receptors on surface of fat, muscle, and liver cells and promote the transport of glucose inside cells. Glucose Transporter 4 triggered by insulin