Ordinary Connective Tissue
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What are 5 functions of connective tissue?
• Extracellular matrix which connects organs and cells • Support • Facilitates cellular defence mechanisms • Repair • Avenue for communication and transport
What are the 2 umbrella classifications of CT?
• Ordinary 2. Connective
What are 3 types of ordinary CT?
• Loose areolar • Dense regular • Dense irregular
Name 5 types of specialised CT
• Adipose tissue • Cartilage • Bone • Dentin • Endothelium
What are 3 structural elements of CT?
• Cells • Fibres • Ground Substance
What are 3 types of fibres present in CT?
• Collagen • Reticular • Elastic
What forms reticular fibres?
Type 3 Collagen
What 4 things make up the ground substance?
• Hydrated gel • GAGs • Proteoglycans • Glycoproteins
What is the principle cell of ordinary CT?
Fibroblast
What 2 things do fibroblasts produce?
• Collagen and elastic fibres 2. Ground substance
What are quiescent fibres known as?
Fibrocyte
What does quiescent mean?
Inactive
Name 2 main features of collagen fibres
• High tensile strength 2. Stretch resistant
Name 2 main features of elastic fibres
• Allows for stretch and recoil 2. Long, thin fibres
Where are reticular fibres usually found?
Vascular organs
How many different types of collagen are there?
Over 25
What is the function of type 1 collagen?
Provide tensile strength
What is the function of type 3 collagen?
First collagen secreted in wound healing
What is the function of type 7 collagen?
Form anchoring fibrils
Where is type 2 collagen found?
Hyaline and elastic cartilage
Where is type 4 collagen found?
Basal lamella
Which type of collagen has a particular affinity for silver salts?
Type 3 - Reticulin
What is the order of formation of molecules to create a collagen fibre?
• Three collagen molecules • Procollagen • Tropocollagen • Collagen fibrils • Collagen fibre
What forms procollagen?
Three individual collagen molecules