Drug Nutrient Interactions
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Methylphenidate (Ritalin)
Anorexia Weight loss Nausea
Amitriptyline/elavil (antidepressant)
Sedative effect, weight gain
Diazepam/Valium (anxiety)
Weight gain
Chlorpromazine/Thorazine (antipsychotic-schizophrenia, manic depression)
Weight gain
Chloridiazepoxide/Librium (anxiety or alcohol withdrawal)
Weight gain
Marinol (tx loss of appetite)
Weight gain
Caproheptadine/periactin (antihistamine)
Weight gain
Megastrol acetate/megace (tx loss of appetite)
Weight gain
Corticosteroids/ prednisone
Weight gain
Lithium carbonate (depression)
Weight gain Increased appetite
MAO inhibitor (depression) Nardil/marplan
Tyramine causes HTN if eaten with MAO inhibitor. Mao inhibitor releases norepinephrine which elevates blood pressure. Restrict intake of tyramine: 1. Avoid aged, fermented, dried, spoiled, smoked, pickled, smoked foods - hard, aged cheese (cheddar, Swiss), sauerkraut, sausages, lunch meats, tofu, miso, Chianti wine 2. Limit sour cream, yogurt, buttermilk 3. Ok: cottage and cream cheeses
Antitubercular INH, isoniazid
B6 Increase intake or supplement Don’t take with food, interferes with vitamin D, calcium, phosphorus
Diuretics / potassium wasting Furosemide, lasix
K, Mg, Ca, Zn Increase intake or supplement
Anticonvulsants Phenytoin, phenobarbital
Folate, vitamin D Increase intake or supplement
Anticoagulants Warfarin/Coumadin
Antagonizes vitamin k Consistent intake essential Avoid ginkgo Bologna extract, garlic, ginger Avoid high doses of vitamin A, E
Corticosteroids Prednisone, cortisone
Suppress inflammation and immune system; decreased bone growth Glucose, calcium Possibly restrict glucose Calcium: supplement
Antidepressants (specifically lithium)
Sodium - maintain consistent intake (along with caffeine) to stabilize levels. If Na or caffeine are restricted, lithium excretion decreases, leading to toxicity
Antiparkinsons (levodopa)
Protein, B6, aspartame - decrease effectiveness Take drug in am with limited protein (
Dextroamphetamine (ADHD, narcolepsy)
Appetite suppressant Anorexia Nausea Weight loss
Methotrexate (antineoplatic)
Folic acid Supplement
Colchicine
Tx gout Increase intake or supplement b12
Antacids
Tx Dyspepsia/peptic ulcer Ca, Fe, Mg, Zn increase intake or supplement
Orlistat
Decreases fat absorption by binding lipase Vitamin/mineral supplementation
Statins (HMG CoA reductase inhibitors)
Decrease LDL,TG Increases HDL