Lecture 12
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What is a virus?
Genetic element that cannot replicate outside a living cell. Have both intracellular, and extracellular form
Virion
Infectious, extracellular virus particle
Virion DNA or RNA genome with a protein coat can have other ____ layers
outer
Virion is metabolically ____ norespiration or ____
Inert/biosynthesis
Virion may contain ____/____ important for infection
proteins/enzymes
Most viruses are smaller than prokaryotic cells
20-300 nm
Usually have only a ____ range of hosts
narrow
Virusis are the most abundant biological particles on earth. T or F
T. Typically found 10x higher concentrations thatn prokaryotic cells
Viruses ____ harm the host
dont always/ some even carry genes that benefit the host
The protein shell that surrounds the genome of a virus particle
Capsid
Capsids can be ____ or icosahedral
helical
Linear or cicular DNA or RNA single stranded or double stranded
Genome
Lipid bilayer surrounding the nuceocapsid
Envelope
Helical symmetry
Rod-shaped viruses
Length of virus determined by length of
Nucleic acid
Width of a virus determined by
sizing of packaging of protein subunits
Icosahedral symmetry
Spherical viruses. Most efficient arrangment of subunits in a cled shell. Quantized 60,180,240,360,420 subunits
Virions composed of several parts, each with seperate shapes and symmetries
Complex viruses ex) icosahedral heads and helical tails
Cellulase, lysozyme, holin
For penetrating host cell surface
Nucleic acid polymerases
Replicating the viral genome
Neuraminadases
enzymes that cleaves glycosidic bonds
Integrase
integration of the virus genome into host cell genome
Viruses that infect bacteria are usaully called
bacteriophages
Most bacterial viruses are
Naked (not enveloped)