Sertoli Cells
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Sertoli cells surround developing cells and nourish which cells until they mature?
Spermatids or haploid sperm cells.
What are the functions of sertoli cells?
• Nourish spermatids (haploid sperm cells) • Blood-testis barrier: between the blood and seminiferous tubules to control entry and exit of hormones, nutrients and other chemicals (protects the sperm cells) • under the influence of testosterone, the Sertoli cells will phagocytize the unnecessary cytoplasm and organelles in the spermatids
What happens when the blood-testis barrier is damaged?
Potential for sperm antibodies to develop, resulting in infertility.
What hormone is released by the Sertoli cells to prevent the sperm cell count from getting too high?
Inhibin, which inhibits the production of FSH by the anterior pituitary gland. It does so by interacting with the pituitary gland and hypothalamus.