eye
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layers of eye
1) fibrous layer- corneosclera 2) vascular layer- has choroid and cilary body, Iris 3) retina- neural and retinal pigment epithelium
ora serrata
non photosensitive region of the retina that lies under the iris and cilary body
Anterior vs posterior segment of the heart
anterior is - -anterior and posterior chambers plus all structures at the front of the eye posterior is- vitreous layer
what is the function of the aqueous humor?
supplies nutrition tx of metabolic waste avascular because don’t want anything getting in the way of light rays entering
Iris
-lots of blood vessel
what are the two structures in the anterior segment of the eye are avascular?
-lens and the cornea = rely on the aqueous layer for nutrition
Uvea
vascular layer of the retina
vitreous humor
• collagen makes it gelatinous - helps keep the retina up on the vascular layer of the choroid
cornea
• part of the corneoscleral coat • anterior 1/6 of eye • provides 2/3 of the refractive power
what are the 5 layers of the cornea?
1) corneal epithelium 2) bowman’s membrane 3) corneal stroma 4) Descemet’s membrane 5) Corneal endothelium
Corneal epithelium
• continuation of the conjunctiva • stratified squamous • attached via desmosomes • lots of mitosis for repair • apex of cells have microvilla that help retain tears secreated- prevents corneal drying • Have FERRITIN to protect DNA from damage to UV light since melanin is absent • innervated by ophthalmic division of 5 -very sensitive
ferritin
protect DNA from damage in the cornial epithelium since it does not have melanin
Bowman’s membrane
• second layer of the cornea (basement membrane) • no regeneration!!! • acellular • terminates at the cornealscleral limbus (where cornea changes over to sclera) • bowman is a tough guy!!!- helps with STRENGTH and STABILITY of the cornea and acts as a barrier to prevent spread of infections to the rest of the eye • if damaged can form an opaque scar which can impair vision (like DAD)
Corneal stroma. How does it become transparent? what makes sure this occurs? what does disruption of the corneal stroma do?
• third layer of the cornea • gives 90% of corneal thickness • transparent based on collagen arrangement in lamellae -right angles • Collagen and V and proteoglycans make sure the correct spacing occurs • disruption of the collagen fibers- make cornea look opaque
Descemet’s membrane
• Fourth layer of the cornea • second basement membrane and basement of the corneal Endothelium • Descemet is one resilient little bitch!- • regenerates after injury and thickens w/ age • interwoven meshwork of fibers and pores • MAINTAINS THE CURVATURE OF THE CORNEA VIA CONNECTIONS WITH SCLERA AND CILIARY MUSCLE- pectinate ligament
Corneal endothelium
• faces ant. chamber of the eyeball • simple squamous joined by ZONA OCCLUDENS (TIGHT JUNCTIONS) and desmosomes • very little proliferation and thus little repair • injury =corneal opacity • RESPONSIBLE FOR VIRTUALLY ALL METABOLIC CHANGES OF THE CORNEA • lots of channels that allow for passage of nutrients fluids
pectinate ligament
• connect the sclera with the desemet’s membrane and allows desemet’s to maintain curvature of the cornea
Sclera- what’s it made of? what does it do? what’s tenon’s capsule?
• made of collagen and elastic fibers • maintains shape of the eyeball • tenon’s capsule- the outer layer of the sclera that is pierced by ocular muscles • sclera pierced by the optic nerve, vessels and blood vessels
Corneal scleral limbus
• where the stem cells for the corneal epithelium are • where the sclera and cornea meet • -WHERE THE IRIDOCHORNEAL (cornea/iris) ANGLE IS underneath the corneal endothelium– how aqueous humor gets into the VENOUS system (constant)-canal of schlem
canal of schlem
how the aqueous humor gets into the venous system (how it’s drained from the eye) located at the corneal scleral limbus (more specifically at the Iridochorneal angle)
what’s the Uvea?
• the vascular coat of the eye (perimeter) • contains the iris and ciliary body -from anterior segment • choroid from posterior segment
Iris
• separates anterior and posterior chambers of the anterior segment of the eye • color part of the eye • middle is the pupil • contractile diaphragm in front of the lens
function of the choroid
-darkly pigmented to prevent glare
Dilator pupilae
contractile diaphragm of iris- sympathetically controlled