States Of Matter
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What is the molecular arrangement of gas - aerosols , inhalers ?
Molecules are far apart
What is the molecular arrangement of liquids such as suspensions, injections?
Molecules are closer together
What is the molecular arrangement of of solid such as tablets and crystalline drugs ?
Molecules are tightly packed
What is the energy and motion of gas such as aerosols and inhalers ?
High energy and rapid random motion
What is the energy and motion of liquids such as injections and solutions ?
Moderate energy and they slide past each other
What is the energy and motions of solids drugs and crystalline solids ?
Low energy and they vibrate in a fixed positions
What is the molecular interaction of gases such as aerosols and interactions ?
Weak interactions
What is the molecular interaction of liquids such as injections and solutions?
Stronger interactions
What is the molecular interaction of solids such as tablets and crystalline drugs ?
Strong intermolecular forces of attraction
What’s the compressibility of gas such as inhalers and aerosols ?
Highly compressible
What’s the compressibility of liquids of solutions and injections ?
Slightly compressible
What’s the compressibility of solids such as tablets and crystalline drugs ?
Incompressible
Why are intermolecular forces good in pharmacy ? DDs
Allows for drug formulation such as tablet compression, powders Stability Drug delivery
What are the 2 opposing forces ?
Attractive and repulsive forces which consistently balance each other out
What are attractive forces ?
They are forces that pull towards each other
What are repulsive forces ?
They are forces that push apart when they get too close
Why are repulsive and attractive forces useful ?
Together they like control physical properties such as density, solubility , vapour pressure and melting and boiling points
What are attractive forces in terms of chemistry?
These are intermolecular forces that hold molecules together
Where do attractive forces arise ?
Electrostatic interactions between charged or polar regions Hydrogen bonding Van der waals
What are attractive bonds responsible for ?
Condensation of gases into liquids Formation of solids to liquids Surface tension Melting and boiling points eg viscosity
What is viscosity ?
Melting or boiling points
Why can glycerol be used as a solvent in cough syrups ?
Glycerol has strong hydrogen bonds so is a thick viscous liquid with a high melting point .
What is the relationship between viscosity and attractive forces ?
The higher and stronger the attractive forces been molecules of a liquid the higher its melting point so more stable in its liquid form
What are repulsive forces in terms of chemistry ?
Theses occur when molecules are pushed too close together