Protien Catabolism & Nitrogenous Waste Excreation
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Functions of EPO?
Anti apoptosis function Produce more RBC 
_____________ recycles HCO3
Kidneys
How can kidney disease lead to lysed RBCs?
Decreased EPO—> anemia and decreased bicarb ——> acidosis ——> causes membrane damage of RBCs and ruptures the cells
What is the most abundant serum protein?
Albumin
What is A:G ratio?
Albumin : total globulin
NPNs… Non-protein
-cholesterol -glucose -urea nitrogen -uric acid -creatinine -iron
Albumin range
3.4-5.0 g/dl
Total globulin range
2.2- 4.0 g/dl
Transferrin
250 mg/dl
Haptoglobin range
30- 205 mg/ dl
Ceruloplasmin range
25-45 mg/dl
Ferritin range
15- 300 ug/ dl
Hemopexin range
50- 100 mg/dl
Cholesterol range
140-250 mg/dl
Glucose range
70- 110 mg/dl
Urea nitrogen
6-23 mg/dl
Uric acid range
4.1- 8.5 mg/dl
Creatinine range
0.7- 1.4 mg/dl
Iron range
50-150 ug/dl
What can be a source of oxidative stress when not bound?
Haptoglobin when not bound to alpha globin chain
Free haptoglobin ______ can tell if if alpha is defective
G
_____________ becomes toxic when not bound
Transferrin
-can bind to free heme -delivered to liver to be recycled
Haptoglobin Hemopexin
Source of NPNs
Amino acids