LESSON 2
No description yet. This curated deck is ready for daily study.
Card preview (24)
This way of naming the enzymes is formulated by IUB and IUPAC.
Standard system
Transcribe IUPAC.
International Union of Pure and Applied Chemistry
This type of naming the enzyme describes the nature of the reaction catalyzed and uses numerical code designation prefixed with the letter “E.C.”
Systematic Name
What does “E.C.” stands for?
Enzyme Commission
If E.C. 3.1.3.1: ALP. How about for ACP?
E.C.3.1.3.2
What is the purpose of using the Numerical Code Designation a.k.a E.C. numbers?
To remove all ambiguity about the enzyme’s identity.
What is the systematic name of LDH?
E.C.1.1.1.27
What digit represents this: “Sub-class: acting on primary and secondary alcohols”
2nd digit
This type of naming is a non-specific, practical and working name. It also used acronyms and abbreviations. What is this?
Trivial name
What is the example of Trivial name?
Serum glutamic oxaloacetic transaminase Serum glutamate pyruvate transaminase
This is a multichained enzymes of similar activity and appear in different tissue, organ and cell organelle of similar organisms.
Isoenzymes
This enzyme identify specific tissue damage and it is structurally different forms of the enzyme but it catalyzes the same reaction.
Isoenzymes
This is produced by the prostate gland and the RBC
Acid Phosphatase
What does H4 (LD1) represents and H3M (LD2) represents?
Heart, RBC and renal tubules
What is the subunit and coefficient of Lungs, lymphocytes and spleen as a group?
H2M2
What is the subunit and coefficient of Liver, and skeletal muscles?
HM3 (LD4) & M4 (LD5)
What does the coefficient of the H & M subunits represent?
The rate of how the isoenzymes migrates in the electrophoresis.
From 1-5 in the “LDH” coefficient. What number is the fastest?
1
What are the characteristics of Isoenzymes?
• Electrophoretic mobility • Mobility in Ion Exchange Resin • Response to inhibition • Relative substrate specificities
Give an example of relative substrate specificities.
ACP (RCB) is less sensitive to a-naphthyl PO4
This is the enzyme that is similar to the catalytic activity but are specie specific.
Heteroenzyme
Give an example of Heteroenzyme.
LDH from Humans and Rabbits
It is a genetically transmitted enzyme and is important in defining the biochemical characteristics of an individual.
Alloenzyme
What is the main application of Alloenzyme?
Forensic and Genetic studies