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Diffusion and partition
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卡片总数: 6 张•内容版本: v4•公开卡包•更新时间: 8/1/2026
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#1
正面 (问题)
what is partition?
背面 (解答)
‘diffusion of drug between two immiscible phases’
#2
正面 (问题)
equation of partition coefficient?
背面 (解答)
P= Co /Cw
#3
正面 (问题)
what does the partition coefficient mostly apply to?
背面 (解答)
drug mostly in its lipophilic form unionised species
#4
正面 (问题)
what is the apparent partition coefficient for solute ionisation in water?
背面 (解答)
Papp= [HA]o / ([HA]w + [A-])
#5
正面 (问题)
what equation is used for weak acids?
背面 (解答)
Log [P/D – 1] = pH - pKa
#6
正面 (问题)
what equation is used for weak bases?
背面 (解答)
Log [P/D – 1] = pKa - pH