Antibiotics

(ANTIBACTERIAL) ✩ Penicillin notatum Mode of Action: Inhibits cell wall synthesis - Narrow spectrum - Targets gram + bacteria ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Development of resistant strains. ↣ B-lactam allergy

(ANTIBACTERIAL) ✩ Cephalosporium spp. Mode of Action: Inhibits cell wall synthesis - Resistant to beta-lactamase - Broad spectrum (+,-) ---------------------------------------- 1st Gen: Mostly Gram + 2nd Gen: Some Gram - and some + 3rd Gen: Some Gram - and +, Pseudomonas ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Development of resistant strains.

(ANTIBACTERIAL) Mode of Action: Inhibits cell wall synthesis - Broad spectrum - Modified Beta-Lactam - Power over 9000! ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Given only through parenteral route ↣ Extremely broad spectrum (LAST RESORT)

(ANTIBACTERIAL) Mode of Action: Inhibits cell wall synthesis - Narrow spectrum, gram + only - Targets MRSA ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Development of resistant strains. (VRSA) ↣ Administered through an IV

(ANTIBACTERIAL) Mode of Action: Inhibits cell wall synthesis - Narrow spectrum - Targets gram + bacteria ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Topical application ONLY (Neosporin)

(ANTIBACTERIAL) Mode of Action: Inhibits synthesis of mycolic acid, prevents bacteria from making the acid. ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIBACTERIAL) Mode of Action: Inhibits synthesis of mycolic acid, prevents mycolic acids from forming on bacterial cell wall. ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIBACTERIAL) Mode of Action: Pokes holes into the cell wall. Leads to lysing of a cell. - Used topically - Targets Gram (-) bacteria ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Used mostly against gram negative and some gram positives - —————————————- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Ototoxicity (hearing loss), nephrotoxicity (Kidney failure)

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Used mostly against gram positive - Used to treat legionnaire’s disease and atypical pneumonia —————————————- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Used as a substitute of penicillin (Non allergenic)

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Broad spectrum - Used in late stages of meningitis ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Rarely used, toxic to children (aplastic anemia) ↣ Bone marrow loss (aplastic anemia)

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - VERY broad spectrum ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Too much can give a patient C-diff (Pseudomembranous colitis) ↣ uh oh stinky

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Broad spectrum ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Kills normal flora, interferes with bone development, turns teeth gray ↣ Used to treat acne

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Broad spectrum ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Kills normal flora, interferes with bone development, turns teeth gray ↣ Used to treat acne

(ANTIBACTERIAL) Mode of Action: Inhibits protein synthesis by blocking the ribosome - Completely synthetic - Affective only against gram + ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIBACTERIAL) Mode of Action: Antimetabolite (Inhibits folic acid production) - Completely synthetic - Competes with bacterial enzymes to block active sites. —————————————- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Trimethoprim + Sulfa drugs = Winnin’ ↣ Used for UTIs and Pneumocystis pneumonia

(ANTIBACTERIAL) Mode of Action: Blocks DNA gyrase - Typically targets Gram (+) cocci and gram (-) bacteria. - Broad spectrum ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Inhibits cartilage development (Not for babies/pregnant women)

(ANTIBACTERIAL) Mode of Action: Inhibits transcription (RNA polymerase) - Targets Tuberculosis - Can penetrate tissue, used to kill Neisseria (meningitis) —————————————- Side Effects/Toxicities/Other: ━━━━━━━━━━━━ ↣ Used in combination with isoniazid and ethambutol to kill TB (mycobacterium tuberculosis) ↣ Red Man Syndrome

• Isoniazid • Ethambutol • Rifampin • Streptomycin

(ANTIVIRAL) Mode of Action: Base analog - Targets Herpes Simplex Virus, and Varicella ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIVIRAL) Mode of Action: Inhibits reverse transcriptase, base analog - Targets HIV - Retroviral infections ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIVIRAL) Mode of Action: Blocks viral uncoating - Targets Influenza ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIVIRAL) Mode of Action: Blocks viral uncoating - Targets HIV ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━

(ANTIVIRAL) - Only created by a cell that has successfully beat an infection - Targets Hep. C ---------------------------------------- Side Effects/Toxicities/Other: ━━━━━━━━━━━━