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Non-Protein Nitrogen Compounds

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

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#1
Front (Question)

Product of analytic methodology requiring removal of protein from sample before analysis

Back (Answer)

Nonportein nitrogen compounds

#2
Front (Question)

NPN compounds are used to

Back (Answer)

Monitor renal or kidney function

#3
Front (Question)

Concentration of nitrogen-containing compounds was quantified spectrophotometrically by converting nitrogen to

Back (Answer)

Ammonia

#4
Front (Question)

Majority of NPN compounds arise from catabolism of

Back (Answer)

Proteins Nucleic acids

#5
Front (Question)

Approximate plasma concentration (% of total NPN)

Back (Answer)

Urea 45-50 Amino Acids 25 Uric Acid 10 Creatinine 5 Creatine 1-2 Ammonia 0.2

#6
Front (Question)

Approximate urine concentration (% of excreted)

Back (Answer)

Urea 86.0 Amino Acids - Uric Acid 1.7 Creatinine 4.5 Creatine - Ammonia 2.8

#7
Front (Question)

NPN with the highest concentration in the blood

Back (Answer)

Urea

#8
Front (Question)

Major excretory product of protein metabolism

Back (Answer)

Urea

#9
Front (Question)

Organ that synthesize urea

Back (Answer)

Liver

#10
Front (Question)

Two forms of urea

Back (Answer)

Blood urea nitrogen (BUN) Urea nitrogen (UN)

#11
Front (Question)

Urea N → Urea concentration

Back (Answer)

Urea N x 2.14

#12
Front (Question)

Clinical function of urea

Back (Answer)

Evaluate renal function Assess hydration status To determine nitrogen balance To aid in the diagnosis of renal disease To verify adequacy of dialysis

#13
Front (Question)

Factors that affect concentration of urea in the plasma

Back (Answer)

Protein content of the diet Rate of protein catabolism Renal function Perfusion

#14
Front (Question)

Urea is reported in terms of

Back (Answer)

Nitrogen concentration

#15
Front (Question)

Chemical Method (Direct Method) for Urea

Back (Answer)

Diacetyl monoxime method

#16
Front (Question)

Substrate of Diacetyl monoxime method

Back (Answer)

Urea + DAM

#17
Front (Question)

Product of Diacetyl monoxime method

Back (Answer)

Yellow Diazine Derivative

#18
Front (Question)

Enzymatic Methods (Indirect Method) for Urea

Back (Answer)

Urease (Urea aminohydrolase) Coupled Urease/ Glutamate Dehydrogenase method

#19
Front (Question)

Proposed reference method for urea

Back (Answer)

Isotope dilution mass spectrometry (IDMS)

#20
Front (Question)

Conversion factor of Urea

Back (Answer)

0.357

#21
Front (Question)

Specimens for urea measurements

Back (Answer)

Plasma Serum Urine

#22
Front (Question)

Fasting sample is required for urea measurements. True or False?

Back (Answer)

False; not required

#23
Front (Question)

Why cant we use citrate and fluoride in plasma when measuring urea?

Back (Answer)

Citrate and fluoride inhibit urease

#24
Front (Question)

Why should we refrigerate urine samples for urea e=measurements?

Back (Answer)

Urea is susceptible to bacterial decomposition