Chapter 4 : Lecture notes
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What is communication between neurons?
A series of events leads to the release of the neurotransmitter into the synaptic cleft.
What organ did Otto Lowei work with?
The heart. He learned that communication could be involved without electrcity. He believed it had to be something chemical. First to prove that it can be chemical
What does voltage tell you?
Voltage- gated Calcium Channels
What are the two types of postsynaptic potentials?
LIgand-gated ion channels
G-protein coupled receptors
Receptors
Different families & types off receptors that each do something different.
What are ionotropic receptors?
What is the difference between excitatory or inhibitory.
Know everything about action potential.
Know concentration inside the cell
Hyperpolarization
Presynaptic
Postysynaptic
Action potential
Amplitude of AP never changes. The frequence changes. Can get to positive dfourties.
AMplitude changes as dunction of activitu
Sensory & afferent nerves.
Pain receptors
Inhibiotry potenital and responses
Regulate activity of the cell
Graded potentials
Graded potentials travel passively & decay. They are not regenterated like action potentials
GP
Move from synapse to axon hillock
Neurotransmitters are terminated by three things. What are they?
• DIffusion: floats away from the synapse • Reuptake: returned to presynaptic neuron • Enyzmatic degradation: Deactivated by an enzyme