ENZYMES OF CLINICAL SGNIFICANCE

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

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Front (Question)

This catalyze interconversions of the amino acids and alpha-ketoaciddds by transfer of amino groups.

Back (Answer)

Aminotransferases

Front (Question)

Give example of Aminotransferases.

Back (Answer)

Pyridoxal phosphate

Front (Question)

What is the significance of Aminotransferases?

Back (Answer)

The products of the reaction of Aminotransferases enters the TCA. Therefore the main significant of AT is production of energy.

Front (Question)

Which is the receiver in an Aminotransferase reaction?

Back (Answer)

Alpha-ketoacids

Front (Question)

What is the function of Aminotransferases?

Back (Answer)

Amino acid metabolism

Front (Question)

What cycle oxidized ketoacids?

Back (Answer)

TCA cycle

Front (Question)

Transcribe SGOT

Back (Answer)

Serum Glutamic Oxaloacetic Transaminase

Front (Question)

What is the reaction catalyzed of AST?

Back (Answer)

Aspartate + a-ketoglutarate <> Oxaloacetate + GLutamate

Front (Question)

This is known to combine with Acetyl Coenzyme A particularly in the first step of the TCA cycle .

Back (Answer)

Oxaloacetate

#10

Front (Question)

What substance is Oxaloacetate known to combine with?

Back (Answer)

Acetyl Coenzyme A

#11

Front (Question)

What is the other importance of Oxaloacetate?

Back (Answer)

It is important in the biomolecule in Gluconeogenesis.

#12

Front (Question)

This is a process where glucose is produced. It is synthesized from nonglucose source.

Back (Answer)

Gluconeogenesis

#13

Front (Question)

What is the product of aspartate when combined with a-ketoglutarate?

Back (Answer)

Oxaloacetate and Glutamate

#14

Front (Question)

This is a carrier of Nitrogen, particularly Ammonia.

Back (Answer)

Glutamate

#15

Front (Question)

This is a waste product of protein.

Back (Answer)

Ammonia

#16

Front (Question)

What is the process of the conversion of Urea?

Back (Answer)

The Glutamate will carry the Ammonia to the liver and in the liver the Ammonia will be converted into Urea.

#17

Front (Question)

The highest concentration of AST can be found in?

Back (Answer)

A. Cardiac tissue B. Liver C. Skeletal muscle

#18

Front (Question)

The smaller amounts of concentration of AST can be found in?

Back (Answer)

A. Kidney B. Pancreas C. RBCs

#19

Front (Question)

What are the types of AST Isoenzyme?

Back (Answer)

A. Mitochondrial Isoenzyme B. Cytoplasmic Isoenzyme

#20

Front (Question)

What are the scientific diagnoses of AST?

Back (Answer)

A.Hepatocellular disorders B. Skeletal muscle involvement

#21

Front (Question)

If it is a mild degree of liver tissue injury, what is predominant?

Back (Answer)

Cytoplasmic Isoenzyme

#22

Front (Question)

What happens if there is a severe tissue damage?

Back (Answer)

Release of mitochondrial Isoenzyme

#23

Front (Question)

Enumerate the AST elevations

Back (Answer)

A. Pulmonary embolism B. Congestive Heart Failure C. Viral hepatitis D. Cirrhosis E. Skeletal muscle disorders

#24

Front (Question)

Define pulmonary embolism

Back (Answer)

Their is a clot in the lungs. Therefore, it blocks the passage of the air which leads to Hypoxia.