Transcription factors
No description yet. This curated deck is ready for daily study.
Card preview (12)
what are transcription factors?
• proteins that control the rate of protein synthesis
How do transcription factors achieve their role?
• By switching some genes on and some genes off
What is the promoter region?
• short sequence of DNA at the start of a gene (the bit that DNA/RNA polymerase attach to)
What are two transcription factors?
• activator • repressor
what happens during transcription?
• Transcription factor moves from the cytoplasm into the nucleus • binds to the promoter region • activators - helps RNA polymerase to bind to DNA • gene is transcribed • Repressors - prevent RNA poymerase binding to DNA • gene is not transcribed
what do the activators do?
• helps RNA polymerase bind to DNA • gene is transcribed
what do the repressors do?
• prevents RNA polymerase binding to DNA • gene is not transcribed
Give an example of controlling a transcription factor?
• Oestrogen
What is Oestrogen?
• a steroid hormone
How is oestrogen controlled as a transcription factor?
• oestrogen binds to a receptor called an oestrogen receptor • forms an oestrogen- oestrogen receptor complex
Is oestrogen an activator or repressor?
• This can depend on the cell
what can transcription factors be turned on/off by?
• second messengers • e.g cAMP