ENDOCRINOLOGY

Network of ductless glands that secrete hormones directly into the blood Considered to be the regulatory system of the body Regulated by means of control of hormone synthesis rather than by degradation

Chemical signals produced by specilized cells, secreted into the blood stream and carried to a target tissues

An increased in the product results to elevation of the activity of the system and the production rate Ex: Gonadal, Thyroidal and Adrenocortical hormone

An increased in the product results to decreased activity of the system and the production rate Ex: Leutenizing Hormone

Secreted in one location and release into blood circulation; binds to specific receptor to elicit physiological response

Secreted in endocrine cells and released into interstitial space; binds to specific receptor in adjacent cell and affects its dunction

Secreted in endocrine cells and released into interstitial space; binds to specific receptor in adjacent cell and affects its function

Secreted in edocrine cells and sometimes released into interstitial space; binds to specific receptor on cell of origin resulting to self-regulation of its function

Secreted in endocrine cells and remains in relation to plasma membrane; acts on immediately adjacent cell by direct cell-to-cell contact

Secreted in endocrine cells and remained as well as function inside the synthesis of origin

Secreted in endocrine cells and released into lumen of gut; affects their function

Secreted in neurons and released into extracellular space; binds to receptor in nearby cell and affects its funciton

Synthesized and stored within the cell in the form of secretory granules and are cleaved as needed Cannot cross the cell membrane due to their large molecular size and thus; produce their effects on the outer surface of the cell

Follicle-Stimulating Hormone HCG Thyroid Stimulating Hormone Erythropoietin

ACTH ADH GH Angiotensin Calcitonin Cholecystokinin Gastrin Glucagon Insulin Melanocyte-Stimulating Hormone Oxytocin PTH Prolactin Somatostatin

Lipid molecules that have cholesterol as a common precurosi Produced by adrenal glands, ovaries, testes and placenta Water insoluble (hydrophobic) and circulate bound to a carrier protein

Derived from an amino acid & they are intermediary between steroid and protein hormones Ex: Epinephrine, Norepinephrine, Triiodothyronine, Thyroxine

Portion of the brain located in the walls and floor of the third ventricle Link between the nervous system and the endocrine system

Hormone TRH Gn-RH GH-IH GH-RH PIF

Attached to the midbrain Secretes melatonin that decreases the pigmentation of the skin Secretions are controlled by nerve stimuli

“Master Gland” Located in a small cavity in the sphenoid bone of the skull called the sella turcica or Turkish saddle Connected by the infundibular stalk to the median eminence of the hypothalamus All pituitary hormones have circadian rhythms

“True Endocrine Gland” Regulates the released and production of hormones Hormones are either peptides or glycoproteins

Secrete growth hormone Immunochemical Test

Secrete prolactin Immunochemical Test