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Coagulation Panel

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卡片总数: 24 张•内容版本: v4•公开卡包•更新时间: 8/1/2026

卡片预览 (24 张)

#1
正面 (问题)

What is included in the tube used to collect blood for a coagulation panel and why?

背面 (解答)

Citrate Stops blood clotting in the tube

#2
正面 (问题)

What 4 things are measured in a coagulation panel?

背面 (解答)

PT, APTT, Fibrinogen, INR

#3
正面 (问题)

What is PT?

背面 (解答)

Prothrombin time /s

#4
正面 (问题)

What is APTT?

背面 (解答)

Activated partial thromboplastin time /s

#5
正面 (问题)

What is fibrinogen measured in?

背面 (解答)

g/L

#6
正面 (问题)

What is INR and what is it used for?

背面 (解答)

an internationally standardised ratio based on PT, technically only valid for warfarin

#7
正面 (问题)

What part of the blood is used to measure the clotting time?

背面 (解答)

Platelet-poor plasma

#8
正面 (问题)

What is the intrinsic pathway order?

背面 (解答)

XII -> XI -> IX -> VIII -> X

#9
正面 (问题)

What is the extrinsic pathway order?

背面 (解答)

VII -> X

#10
正面 (问题)

What is the common pathway order?

背面 (解答)

X -> Xa Prothrombin (FII) -> Thrombin (FIIa) Fibrinogen (FI) -> Fibrin clot

#11
正面 (问题)

What are DOACs?

背面 (解答)

Direct-acting oral anticoagulants

#12
正面 (问题)

Which clotting factor do apixaban, rivaroxaban and edoxaban act on?

背面 (解答)

Factor X

#13
正面 (问题)

Which clotting factor does Dabigatran work on?

背面 (解答)

Thrombin

#14
正面 (问题)

How do DOACs affect coag panel tests?

背面 (解答)

Variable non-linear impact on PT and APTT

#15
正面 (问题)

What coagulation factors does warfarin inhibit?

背面 (解答)

IX, VII, X, Prothrombin (II)

#16
正面 (问题)

How does warfarin work to inhibit coagulation factors?

背面 (解答)

Inhibits the synthesis of vitamin K dependent clotting factors

#17
正面 (问题)

What else does warfarin inhibit the synthesis of?

背面 (解答)

Protein S and C

#18
正面 (问题)

How does warfarin affect coagulation panels?

背面 (解答)

Affects PT and APTT PT is particularly sensitive - INR used to monitor dosage

#19
正面 (问题)

What are heparins?

背面 (解答)

naturally occuring sulphated glycosaminoglycans isolated from animal tissue - usually porcine intestine

#20
正面 (问题)

How do heparins inhibit blood coagulation?

背面 (解答)

Potentiating the effect of antithrombin Accelerates the inactivation of thrombin and factor Xa

#21
正面 (问题)

What can unfractionated heparin bind to?

背面 (解答)

antithrombin and thrombin

#22
正面 (问题)

How is unfractionated heparin administered?

背面 (解答)

Intravenously Loading dose required before continuous infusion Careful monitoring needed

#23
正面 (问题)

What does low molecular weight heparin bind to?

背面 (解答)

Antithrombin

#24
正面 (问题)

How is low molecular weight heparin administered?

背面 (解答)

Subcutaneous injection Weight dependent dosage