Hemostasis
No description yet. This curated deck is ready for daily study.
Card preview (9)
What is Hemostasis?
• Process which blood vessels are repaired • Occurs in 4 stages
What is the 1st stage of Hemostasis?
Vascular Phase: Blood vessel constricts slowing blood flow
What is the 2nd stage of Hemostasis?
• Platelet Phase: Platelets adhere to endothelial lining. • Aggregation: Temporary platelet plug forms
What are the primary phases of primary hemostasis?
• Vascular and Platelet phase • Bleeding time test evaluates primary hemostasis
What is the 3rd stage of Hemostasis?
• Coagulation Phase: Cascade of coagulation factors that convert temporary platelet plug to a stable fibrin clot.
How does the coagulation cascade work?
• Has intrinsic system and extrinsic system • Systems come together in a common pathway
What is Activated Partial Thromboplastin time? (APTT)
• Test used to evaluate intrinsic pathway. • Used to monitor heparin therapy.
What is Prothrombin time (PT)?
• Test used to evaluate extrinsic pathway. • Used to monitor coumadin therapy.
What is the 4th stage of Hemostasis?
• Fibrinolysis: Breakdown and removal of clot. • When tissue repair starts, plasim enzyme, breaks down fibrin in the clot • Fibrin degradation products (FDPs) amount is used to monitor rate of fibrinolysis.