test 3

what is the most established example of an approved anti-cancer targeted drug

what oncoprotein does gleevec target

BCR-ABL is the main driver oncoprotein for what cancer

— are cancers involving WBCs of marrow and blood

leukemias are categorized as either – or –

in – leukemias, the cancer cells are partially differentiated

in – leukemias, the cancer cells show little differentiation

– are cancers involving the lymphocytes and lymph system

where are pluripotent hemopoietic stem cells located?

t or f: excessive reproduction of the common myeloid precursor may reduce the number of platelets and erythrocytes

what two progenitors come from the pluripotent hemopoietic progenitor

where do the committed progenitors for blood cell formation do most of their development

t or f: excessive reproduction of the common lymphoid precursor may reduce the number of mature B cells and T cells

chronic myeloid leukemia is characterized by uncontrolled proliferation of – and precursors

t or f: excessive reproduction of the common lymphoid precursor may reduce the number of mature platelets and erythrocytes

what is the only known risk factor for chronic myeloid leukemia

CML represents about –% of new leukemia cases

average age for developing chronic myeloid leukemia is –

you can tell that a neutrophil is mature by the appearance of –

immature neutrophils are called –

how many clinical phases does chronic myeloid leukemia have

what are the 3 clinical phases of chronic myeloid leukemia

which phase of CML is <5% blasts? chronic, accelerated, or crisis

which phase of CML is 10-19% blasts? chronic, accelerated, or crisis