PICLEC: MODULE 3
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OFFICIAL ACIDS: Treatment of gastric achlorhydria (lack of hcl)
DILUTED HYDROCHLORIC ACID
Arsenic chloride soution
ARSENIOUS ACID
“Nitromuriatic acid”, “aqua regia” — kingly water
NITROHYDROCHLORIC ACID
“Eau forte”, “Aqua fortis”— Strong water
NITRIC ACID
used for manufacturing explosives and nitrates. (act as preservative)
NITRIC ACID
OFFICIAL ACIDS
HYDROCHLORIC ACID NITRIC ACID PHOSPHORIC ACID SULFURIC ACID BORIC ACID
“Monsel’s solution”
FERROUS SUBSULFATE SOLUTION
the nitric acid converts the bismuth subnitrate to nitrate
BISMUTH MAGMA
Hydrochloric acid sub solutions
HYDROCHLORIC ACID DILUTED HYDROCHLORIC ACID ARSENIOUS ACID NITROHYDROCHLORIC ACID
nitric acid sub solutions
FERROUS SUBSULFATE MERCURIC NITRATE SOLUTION BISMUTH MAGMA
Phosphoric acid sub solutions
PHOSPHORIC ACID USP (85-88% of H3PO4) DILUTED PHOSPHORIC ACID (9.5-10.5 % of H3PO4)
Sulfuric acid sub solutions
SULFURIC ACID USP ( 94-95% H2SO4) SACCHARATED FERROUS CARBONATE (diluted H2SO4)
Boric acid sub solutions
KAOLIN CATAPLASM BORIC ACID SOLUTION BORIC ACID OINTMENT LISTER’S SOLUTION (antiseptic solution) COMPOUN ZINC SULFATE POWDER (Antiseptic powder)
OFFICIAL BASES
SODIUM HYDROXIDE POTASSIUM HYDROXIDE CALCIUM HYDROXIDE SODIUM CARBONATE STRONG AMMONIA SOLUTION DILUTED AMMONIA SOLUTION
Used as standard solution in acid-base titrations
SODIUM HYDROXIDE
Similar to NaOH, more deliquescent, stronger and more expensive
POTASSIUM HYDROXIDE
Mixture of compounds, resists pH changes upon addition of small quantities of acid or alkali maintain pH of medicinals at optimal limits
BUFFERS
Used in formulation of opthalmic solutions
PHARMACEUTICAL BUFFERS
sodium phosphate + NaCl (pH 6-8) “Phosphate buffered saline”
sorensen phosphate buffer
boric acid + sodium carbonate +KCL
GIFFORD’S BUFFER
Boric acid + sodium carbonate + NaCl
ATKIN’S AND PANTIN BUFFER
Boric acid + sodium BORATE + NaCl
FELDMAN’S BUFFER / PALITZSCH BUFFER
Raw material, inactive ingredients, medicinal vehicle, solvent
Water
Manufacture of pharmaceutical products, active pharmaceutical ingredients, APIs intermediates, compedial articles, and analytical Reagents as well as cleaning applications
Water