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15. Lipid Metabolism, Pathophysiology and Lab Tests

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (24)

#1
Front (Question)

3 components of a chylomicron

Back (Answer)

• Cholesterol • Phospholipids • Protein (coat)

#2
Front (Question)

Effect of insulin on lipolysis?

Back (Answer)

Deceases lipolysis by reducing conversion of fat cell lipid stores into blood fatty acids

#3
Front (Question)

What is linolenic acid an example of?

Back (Answer)

Polyunsaturated FA

#4
Front (Question)

What is analyzed in the precipitation separation method for HDL measurement?

Back (Answer)

The SUPERNATANT is analyzed for HDL

#5
Front (Question)

More common method of HDL measurement?

Back (Answer)

Homogenous enzymatic colorimetric mehod

#6
Front (Question)

Effect of insulin on lipid synthesis?

Back (Answer)

Increases lipid synthesis (forces fat cells to take in blood lipid => converted to trigs)

#7
Front (Question)

Cause of turbid bottom layer

Back (Answer)

VLDL

#8
Front (Question)

Which apolipoprotein to test in the lab for HDL?

Back (Answer)

A1

#9
Front (Question)

When chyme enters duodenum, it triggers a hormonal signal called _________

Back (Answer)

Cholecystokinin

#10
Front (Question)

Causes a cream layer on top of plasma after overnight refrigeration

Back (Answer)

Chylomicrons (lowest density)

#11
Front (Question)

Main function of apolipoproteins?

Back (Answer)

Direct lipids to correct target

#12
Front (Question)

What does a turbid sample indicate?

Back (Answer)

Trig levels > 4 mmol/L

#13
Front (Question)

Liver synthesis of trigs - 2 sources?

Back (Answer)

• FAs in adipose tissue - Carbs from diet

#14
Front (Question)

Triglycerides RI

Back (Answer)

< 1.70 mmol/L

#15
Front (Question)

Hormone sensitive lipase activity is promoted by ________ and inhibited by _________

Back (Answer)

Promote - growth hormone Inhibit - insulin

#16
Front (Question)

What is familial hypecholesterolemia? Consequences?

Back (Answer)

Defective LDL receptor = no LDL internalization Leads to atherosclerotic plaque formation

#17
Front (Question)

4 functions of cholesterol

Back (Answer)

• Cell membranes • Precursor of bile acids • Precursor for all steroid hormones • Vitamin D

#18
Front (Question)

____________ cannot be synthesized in the human body

Back (Answer)

Essential fatty acids

#19
Front (Question)

Main function of trigs?

Back (Answer)

Provide energy for cells and component of cell membranes

#20
Front (Question)

4 forms FAs can exist as

Back (Answer)

• Free fatty acids • Triglycerides • Phospholipids • Cholesterol esters

#21
Front (Question)

What do patients w/ primary hyperlipidemia develop

Back (Answer)

Xanthomas

#22
Front (Question)

Function of cholecystokinin

Back (Answer)

Triggers gall bladder release of bile into duodenum

#23
Front (Question)

Which apolipoprotein to test in the lab for LDL?

Back (Answer)

B100

#24
Front (Question)

Difference between abetalipoproteinemia and dysbetalipoproteinemia

Back (Answer)

Abeta- = Defective apoprotein B synthesis Dysbea- = defect in Apo-E synthesis