Lecture 7
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Carbohydrates
contain carbon, hydrogen, and oxygen Contain a carbonyl group and several hydroxyl groups
What is the general formular for Carbohydrates?
Cx(H2O)y
D-glucose
seen in nature rotates plane polarized light clockwise
L-Glucose
mirror opposite of D-Glucose manufactured in a lab setting rotates plane polarized light counter-clockwise
The OH group of D and L-glucose determines what?
determines the “handedness” of both forms
Monosaccharides
Simplest of carbohydrates or sugars, Cannot be hydrolyzed any further made up of three to seven carbons can exist as a linear chain or as ring-shaped molecules
What are the common Monosaccharides?
Glucose, Galactose, and Fructose are monosaccharide isomers
What differs the monosaccharide isomers?
same chemical formula but differ structurally and chemically
Glucose
popular monosaccharide used in the body as a source of energy
How much glucose is in blood?
4 g of Glucose
How much glucose does the brain absorb?
120 g glucose daily ~ 60% - 70%, is used to power transport mechanisms that maintain the Na+-K+ membrane potential required for the transmission of the nerve impulses
Monosaccharide locations
D-Glucose = Blood sugar D-Galactose = Milk sugar (part of lactose) D-Fructose = Fruit sugar
What else is considered a monosaccharide?
DNA and RNA
Disaccharides
Comprised of 2 monosaccharides Broken down by hydrolysis reactions
Disaccharide types
Maltose + H2O -> 2 glucose Lactose + H2O -> glucose + galactose Sucrose + H2O -> glucose + fructose
Polysaccharides
3 or more monosaccharides
What are the Polysaccharide linkages?
Alpha: digestible by humans, found in most carbohydrates Beta: not digestible by humans, fiber
Starch
glucose units bound by Alpha linkages
Cellulose
○ of glucose units bound by Beta linkages Corn is a good example
What must happen to Polysaccharides before it is absorbed?
must be hydrolyzed to monosaccharides
What catalyzes the hydrolysis reaction of Polysaccharides?
Amylases in the mouth and stomach
What happens to fructose and galactose during absorption?
Both are converted into glucose
Where are carbohydrates stored?
Stored as glycogen in liver and muscles
What is glycogen?
highly branched polysaccharide of glucose