test 4

these are all considered — lack of nucleotides, UV radiation, ionizing radiation, oncogene signalling, hypoxia, blockage of transcription

if there is no functional p53, cells will — damaged DNA fail to undergo —

responses to cell stress stimuli rely on gene expression by —

what circumstances are severe enough that they will cause the cell to undergo apoptosis

what type of cell is 95% of the population routinely “killed” through apoptosis

what cellular process allows amphibians to go through metamorphosis

what organelle plays a major role in apoptosis

what protein moves from the mitochondria to the cytosol during apoptosis

is bcl-2 pro-survival or pro-apoptosis

is the Bax family pro-survival or pro-apoptosis

pro-survival and pro-apoptosis proteins regulate cytochrome c movement through — in the mito outer membrane

— promotes Bax expression `

p53 promotes pro-apoptosis or pro-survival route?

Akt/PKB phosphorylates and inactivates —

is Bad pro-survival or pro-apoptosis

when Bad is phosphorylated, it is (activated/inactivated)

what protein kinase inactivates Bad

is Akt/PKB pro-survival or pro-apoptosis

when Noxa, Puma, Bad, Hrk, Bim, Bmf, and Bik are activated, they all inactivate —

when Bcl-2 is inactivated, —- (the main pro-apoptotic proteins) can induce apoptosis

true or false: Bcl-2 is a tumor suppressor

the apoptotic cascade is done by — (protease type)

Smac/DIABLO inhibit —-

are Smac/DIABLO pro-survival or pro-apoptosis